Clinical trials
This is a list of current clinical trials that may be of
interest to women with ovarian cancer.
To learn more about the trials, click on the link to be taken to
the trial page. If you would like to discuss any aspect of clinical
trials in general, please call us on 0845 371 0554 to speak to a
nurse.
DNA Methylation
A trial to see if cell changes can help tell doctors who will
respond to chemotherapy for ovarian cancer.
ICON6
A trial to see if whether adding a new drug Cediranib to standard
treatment is beneficial in patients where the disease has returned
more than 6 months after the intial treatment.
HOT11
This is a trial to see if giving oxygen therapy in a special way
(hyperbaric) can help people who have suffered from long term side
effects from radiotherapy damage to the pelvis.
AG-014699
A trial looking at a new drug for breast and ovarian cancer, in
people with BRCA gene faults.
Gem-TIP
This trial is to find out more about giving the chemotherapy drugs
gemcitabine (Gemzar), paclitaxel (Taxol), ifosfamide and cisplatin
for advanced germ cell cancer that has come back (relapsed).
mEOC
This trial is comparing 2 different chemotherapy combinations with
or without bevacizumab (Avastin) for a rare type of ovarian cancer
called mucinous epithelial ovarian cancer.
SaPPrOC
A study looking at Paclitaxel with or without Saracatinib for
ovarian, fallopian tube or primary peritoneal cancer that has come
back.
ICON8
A trial looking at weekly chemotherapy for ovarian cancer
NKTR-102
A trial of NKTR-102 for advanced ovarian cancer that is resistant
to platinum drugs
Biomarkers
A study looking at using biomarkers to help doctors choose suitable
treatment for women with ovarian or womb cancer
Mercaptopurine and Methotrexate
This trial is looking at 2 chemotherapy drugs called mercaptopurine
and methotrexate. It is for people with an inherited fault in the
BRCA1 or BRCA2 gene who have locally advanced or secondary breast
cancer, or advanced ovarian cancer that has come back after other
treatment
Borderline ovarian tumours
This study is looking at tissue samples and clinical information to
learn more about borderline ovarian tumours and how to improve
treatment.
PETROC
A trial comparing different combinations of chemotherapy after
surgery for women with ovarian cancer who have already had
chemotherapy before surgery.